When it's hard to breathe, maybe pain doesn't matter. Focus on "Dyspnea as a noxious sensation: inspiratory threshold loading may trigger diffuse noxious inhibitory controls in humans".
نویسندگان
چکیده
Robert B. Banzett, Richard H. Gracely, and Robert W. Lansing Department of Medicine, Harvard Medical School; Division of Pulmonary and Critical Care, Beth Israel Deaconess Medical Center; and Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, Massachusetts; and Departments of Internal Medicine-Rheumatology and Neurology, University of Michigan Health System, Veterans Affairs Medical Center, Ann Arbor, Michigan
منابع مشابه
Dyspnea as a noxious sensation: inspiratory threshold loading may trigger diffuse noxious inhibitory controls in humans.
Dyspnea, a leading respiratory symptom, shares many clinical, physiological, and psychological features with pain. Both activate similar brain areas. The neural mechanisms of dyspnea are less well described than those of pain. The present research tested the hypothesis of common pathways between the two sensations. Six healthy men (age 30-40 yr) were studied. The spinal nociceptive flexion refl...
متن کاملSupraspinal modulation of trigeminal nociception and pain.
OBJECTIVE This study examined modulation of trigeminal pain/nociception by 2 supraspinal mechanisms: emotional controls of nociception and diffuse noxious inhibitory controls. BACKGROUND Prior research suggests emotional picture viewing (emotional controls) and tonic noxious stimuli (diffuse noxious inhibitory controls) engage supraspinal mechanisms to modulate pain and nociceptive processes....
متن کاملChemical ablation of the hypothalamic arcuate nucleus and its effect on electroencephalographic tracings and pain threshold in the tail flick test
The present study was carried out to explore the possible involvement of the arcuate nucleus of the hypothalamus in the inhibitory descending pain control system associated with the tail flick test and EEG recordings. Adult male (NMRI) albino rats weighing 200 ± 20 g were used. Rats were divided into three groups: experimental, sham and control. The arcuate nucleus was destroyed unilaterally ...
متن کاملDoes Acupuncture Needling Induce Analgesic Effects Comparable to Diffuse Noxious Inhibitory Controls?
Diffuse noxious inhibitory control (DNIC) is described as one possible mechanism of acupuncture analgesia. This study investigated the analgesic effect of acupuncture without stimulation compared to nonpenetrating sham acupuncture (NPSA) and cold-pressor-induced DNIC. Forty-five subjects received each of the three interventions in a randomized order. The analgesic effect was measured using pres...
متن کاملDescending controls: how to harness for the relief of pain?
Descending control of spinal nociception, which originates in many brain regions, is a major determinant of the pain experience. Descending control is dynamic and can either depress or enhance spinal nociceptive signalling depending on where it originates or what triggers it (Heinricher et al. 2009). A major challenge for therapeutic utility, whether that be engaged by physical or chemical mean...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of neurophysiology
دوره 97 2 شماره
صفحات -
تاریخ انتشار 2007